What is A/G Ratio?
The A/G ratio compares albumin with globulin and is usually interpreted together with total protein and other liver- or inflammation-related markers.
The A/G ratio is calculated, not directly measured. It is most informative when read together with albumin, globulin, and total protein.
Why might A/G Ratio be low?
A low A/G ratio can be seen with chronic inflammation, certain liver conditions, or with elevated globulin from other causes. Diagnosis usually requires confirmation and clinical context.
This information is educational. A single out-of-range result is rarely the whole picture — a healthcare professional can interpret your numbers alongside your overall health and history.
Context questions that matter
- →Was this result slightly or clearly outside the reference range?
- →Were related markers also high or low?
- →Is this new compared with previous tests?
- →Could recent illness, exercise, fasting, alcohol, supplements, or medication affect it?
- →Do you have symptoms that should be discussed with a clinician?
Markers often reviewed together with A/G Ratio
Clinicians rarely look at one number in isolation. These markers usually accompany A/G Ratio on a liver function panel and help put the result in context.
Questions to ask your doctor
- →Could any medication, supplement, alcohol intake, or recent intense exercise affect this low A/G Ratio result?
- →Should we compare this with ALT, AST, GGT, ALP and bilirubin together?
- →Is this a single abnormal value, or part of a broader liver-marker pattern?
Don't guess from one flagged result.
Start with the most relevant panel and see how your markers fit together in plain English.
Frequently asked questions
What does low A/G Ratio mean?
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A low A/G ratio can be seen with chronic inflammation, certain liver conditions, or with elevated globulin from other causes. Diagnosis usually requires confirmation and clinical context.
What is A/G Ratio?
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The A/G ratio compares albumin with globulin and is usually interpreted together with total protein and other liver- or inflammation-related markers.
Can exercise, alcohol or medication affect A/G Ratio?
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They can sometimes affect liver-related markers. A/G Ratio is usually read with ALT, AST, GGT, ALP and bilirubin together with your recent context — recent intense exercise, alcohol intake, prescription medications and supplements all matter. One result alone cannot diagnose a condition.
Which liver markers should I compare with A/G Ratio?
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Common companions on a liver panel include ALT, AST, GGT, ALP, total bilirubin and direct bilirubin. The pattern across these markers is usually more informative than any single value — for example, GGT helps separate liver-side from bone-side raised ALP, and the AST:ALT ratio gives context for liver-enzyme elevation.