What this marker measures
TG antibodies are often ordered together with TPO antibodies in autoimmune thyroid workups, and tracked separately after thyroidectomy for cancer.
High or low: what it can mean
High TG Antibodies
Elevated TG antibodies are seen in Hashimoto's thyroiditis and Graves' disease. After thyroid cancer surgery, they are monitored because they can interfere with thyroglobulin tumour-marker testing.
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Low TG Antibodies
A negative (low) result is normal and reduces the likelihood of autoimmune thyroid disease. Mild positivity in otherwise-healthy people is common and usually requires only periodic follow-up.
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Frequently asked questions
What is TG Antibodies?
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TG antibodies are autoantibodies against thyroglobulin, a protein the thyroid uses to make hormones. They are a marker of autoimmune thyroid disease and are also tracked after thyroid cancer treatment.
What does TG Antibodies measure?
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TG antibodies are often ordered together with TPO antibodies in autoimmune thyroid workups, and tracked separately after thyroidectomy for cancer.
What does high TG Antibodies mean?
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Elevated TG antibodies are seen in Hashimoto's thyroiditis and Graves' disease. After thyroid cancer surgery, they are monitored because they can interfere with thyroglobulin tumour-marker testing.
What does low TG Antibodies mean?
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A negative (low) result is normal and reduces the likelihood of autoimmune thyroid disease. Mild positivity in otherwise-healthy people is common and usually requires only periodic follow-up.
Related biomarkers
Editorial note
LabTestly explains lab markers using plain-English educational content. Reference ranges may vary by laboratory and should be interpreted with a clinician.
Educational content · Editorially reviewed for clarity · Last updated
Common sources used for lab-test education
Not medical advice
This page is for general understanding only and does not replace medical advice from your clinician. Reference ranges can vary by laboratory, age, sex, pregnancy status, medications, and clinical context.