What this marker measures
A mid-luteal progesterone level (around day 21 of a 28-day cycle) is the classic way to confirm ovulation. Values must always be interpreted relative to the cycle phase.
High or low: what it can mean
High Progesterone
Elevated progesterone outside pregnancy is uncommon; it can occur with ovarian cysts or congenital adrenal hyperplasia. During the luteal phase a normal rise confirms ovulation.
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Low Progesterone
Low luteal-phase progesterone may indicate anovulation. Low progesterone is expected in the follicular phase and after menopause.
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Frequently asked questions
What is Progesterone?
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Progesterone is a steroid hormone produced mainly by the ovaries (and in large amounts by the placenta during pregnancy). It prepares the uterus for implantation and supports early pregnancy.
What does Progesterone measure?
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A mid-luteal progesterone level (around day 21 of a 28-day cycle) is the classic way to confirm ovulation. Values must always be interpreted relative to the cycle phase.
What does high Progesterone mean?
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Elevated progesterone outside pregnancy is uncommon; it can occur with ovarian cysts or congenital adrenal hyperplasia. During the luteal phase a normal rise confirms ovulation.
What does low Progesterone mean?
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Low luteal-phase progesterone may indicate anovulation. Low progesterone is expected in the follicular phase and after menopause.
Related biomarkers
Editorial note
LabTestly explains lab markers using plain-English educational content. Reference ranges may vary by laboratory and should be interpreted with a clinician.
Educational content · Editorially reviewed for clarity · Last updated
Common sources used for lab-test education
Not medical advice
This page is for general understanding only and does not replace medical advice from your clinician. Reference ranges can vary by laboratory, age, sex, pregnancy status, medications, and clinical context.